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  1. November 10, 2017. Apurinic/apyrimidinic endonuclease APE1 is required for... (http://www.pnas.org/content/107/7/3204.full) CRT0044876 is a potent and selective APE1... Natural Products;... Gemcitabine has been used to treat pancreatic cancer and has demonstrated effective anti-tumor...
  2. ape1 tumor natural products picture 1
  3. November 3, 2017. Identification of a novel potential antitumor activity of... (https://www.dovepress.com/identification-of-a-novel -potential-antitumor-activity-of-gossypol-as peer- reviewed-fulltext-article-DDDT) Scoparone, a natural compound isolated from Artemisia capillaris, has been used in Chinese herbal medicine to treat neonatal jaundice. Signal transducer and activator...
  4. ape1 tumor natural products picture 2
  5. November 8, 2017. CRT0044876 | DNA/RNA Synthesis inhibitor | Read Reviews... (http://www.selleckchem.com/products/crt0044876.html) ARYLSTIBONIC ACIDS Lauren A. Seiple... and Natural Products Support Group SAIC, Inc... 1994; Wang et al., 2004). Tumor promotion by Ape1 has not only been shown
  6. ape1 tumor natural products picture 3
  7. November 11, 2017. Identification of a novel potential antitumor activity of... (http://europepmc.org/articles/PMC4026309) Synthetic lethal targeting of DNA double strand break repair deficient cells by human apurinic/apyrimidinic endonuclease (APE1) inhibitors
  8. November 5, 2017. APE1/Ref-1 enhances DNA binding activity of mutant p53 in... (http://www.spandidos-publications.com/or/31/2/901) OGG1 products; Apex1 products; XRCC3 products;... (APE1) in osteosarcoma tumor cell resistance and prognosis... (APEX1/APE1) polymorphisms and...
  9. ape1 tumor natural products picture 5
  10. November 9, 2017. Synthetic lethal targeting of DNA double strand break... (http://pubmedcentralcanada.ca/pmcc/articles/PMC3742 328/) Journal of Natural Products;... of Small-Molecule Human Apurinic/Apyrimidinic... to resistance of tumor cells to radio- and chemotherapy. APE1 also shows...
  11. ape1 tumor natural products picture 6
  12. November 14, 2017. Soy Isoflavones Augment Radiation Effect by Inhibiting... (http://www.sciencedirect.com/science/article/pii/S1 556086415333827) Also APE1 is showed high expression on the tumor tissues of... The work was supported by the National Natural Science... Human apurinic endonuclease 1 (APE1)...
  13. ape1 tumor natural products picture 7
  14. November 12, 2017. Upregulation of PD-L1 and APE1 is associated with... (http://europepmc.org/articles/PMC4338255) Apurinic/apyrimidinic endonuclease APE1 is required for PACAP-induced neuroprotection against global cerebral ischemia
  15. November 16, 2017. APE1 promotes antioxidant capacity by regulating Nrf-2... (http://www.sciencedirect.com/science/article/pii/S0 891584914004559) Cleaving the oxidative repair protein Ape1 enhances cell death mediated by... and natural killer... The reaction products were analyzed by Ape1 immunoblot...
  16. ape1 tumor natural products picture 9
  17. November 15, 2017. Experimental & Molecular Medicine - APE1/Ref-1 as an... (http://www.nature.com/articles/emm201442) Soy Isoflavones Augment Radiation Effect by Inhibiting APE1... resulting in enhanced cell killing and tumor growth inhibition. 7,9,10 APE1... shows the products...
  18. ape1 tumor natural products picture 10
  19. November 4, 2017. APEX1 - Labome.Org (https://www.labome.org/gene/human/apex1-328.html) Functional analysis of the involvement of apurinic/apyrimidinic endonuclease 1... overexpression of APE1 in tumor tissues... of the reaction products from...
  20. ape1 tumor natural products picture 11
  21. November 2, 2017. Downregulation of APE1/Ref-1 Is Involved in the Senescence... (http://onlinelibrary.wiley.com/doi/10.1002/stem.54/ full) You have free access to this content Synthetic lethal targeting of DNA double-strand break repair deficient cells by human apurinic/apyrimidinic endonuclease inhibitors
  22. November 17, 2017. Redox Factor-1 Mediates Inflammatory Response during Tumor... (http://file.scirp.org/Html/23586.html) APE1 promotes antioxidant capacity by regulating Nrf-2... of the reaction products from... Higher expression levels of APE1 in most tumor cells have...
  23. ape1 tumor natural products picture 13
  24. November 18, 2017. The DNA Repair Gene APE1 T1349G Polymorphism and Risk of... (http://journals.plos.org/plosone/article?id=10.1371 /journal.pone.0028971) into how APE1/Ref-1 may affect early stage tumor pro-... ntion by utilizing known antioxidant-inducing natural. products to determine whether antioxidant expression.
  25. ape1 tumor natural products picture 14
  26. November 7, 2017. Pharmacophore Guided Discovery of Small-Molecule Human... (http://pubs.acs.org/doi/pdfplus/10.1021/jm800739m) Effect of APE1 on p53 DNA binding activity by EMSA. (A)... and APE1 could enhance DNA binding activity of... whereas downregulation of APE1 can enhance tumor...
  27. ape1 tumor natural products picture 15
  28. November 19, 2017. APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 [ (human)] (https://www.ncbi.nlm.nih.gov/gene/328) Overexpression of APE1 and enhanced AP endonuclease activity have been linked to increased resistance of tumor cells to... Journal of Natural Products; The...
  29. November 13, 2017. Human Apurinic/Apyrimidinic Endonuclease siRNA Inhibits... (http://www.medsci.org/v10p0870.htm) The use of natural agents in cancer... in the prevention of tumor progression... natural products in cancer chemoprevention and chemotherapy...
  30. ape1 tumor natural products picture 17
  31. November 6, 2017. NIH Public Access ARYLSTIBONIC ACIDS Mol Pharmacol (https://www.researchgate.net/profile/Rhone_Akee2/pu blication/5804636_Potent_Inhibition_of_Human_Apurin icApyrimidinic_Endonuclease_1_by_Arylstibonic_Acids /links/0046353b4186210836000000/Potent-Inhibition-o f-Human-Apurinic-Apyrimidinic-Endonuclease-1-by-Ary lstibonic-Acids.pdf) Human apurinic endonuclease-1 (APE1)... role as a metastasis suppressor in tumor... products from AP endonuclease activity assay were resolved on a...
  32. ape1 tumor natural products picture 18
  33. November 1, 2017. Scoparone Exerts Anti-Tumor Activity against DU145... (http://www.oalib.com/paper/3010929) Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP

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